ANTIHIPERGLICEMIC THERAPY COMPLIANCE WITH HbA1C LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS AMONG PEKANBARU PROLANIS PARTICIPANTS

Dimas Pramita Nugraha, Eni Karmila Asni, Ligat Pribadi Sembiring Pribadi Sembiring

Abstract


One of the pillars in the management of Type 2 Diabetes Mellitus (DM) is pharmacotherapy, i.e. the use of antihyperglycemic drugs. Success in DM management is influenced by patient compliance to the pharmacotherapy given. One indicator of controlling Type 2 DM is HbA1c levels. This study aimed to analyze the relationship between antihyperglycemic therapy compliance and the HbA1c levels in Type 2 DM patients in the Chronic Disease Management Program in Pekanbaru. Method. This was a cross-sectional study. Samples were taken by consecutive sampling method. Laboratory examination was carried out to obtain HbA1c levels, the value of which was categorized controlled if <7%. The compliance with the use of antihyperglycemic drugs was assessed using Medication Possession Ratio (MPR). Patients were considered compliant if they had an MPR of ≥80%. Data were analyzed using the Fisher Exact test. Results. Most of the 48 patients had uncontrolled HbA1c levels (87,5%). The level of non-compliant patients was also very high (91,7%). This study showed a significant relationship between pharmacotherapy compliance and HbA1c levels (p <0.05). Discussion. There was a relationship between pharmacotherapy compliance and the level of HbA1c in Type 2 DM patients.  Physicians should pay more attention to patients with low compliance as it may increase the risk to a high HbA1c level

DOI:

https://doi.org/10.30596/bf.v5i1.4203


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References


Kementerian Kesehatan Republik Indonesia. Riset Kesehatan Dasar. 2018.

PERKENI, Konsensus Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 di Indonesia. PB.PERKENI. Jakarta 2015.

Lin L-K, Sun Y, Heng BH, Chew DEK, Chong PN et al. Medication adherence and glycemic control among newly diagnosed diabetes patients. BMJ Open Diab Res Care. 2017;5

Nichols GA, Rosales AG, Kimes TM, Tunceli K, Kurtyka K, Mavros P et al. The Change in HbA1c Associated with Initial Adherence and Subsequent Change in Adherence among Diabetes Patients Newly Initiating Metformin Therapy. Journal of Diabetes Research Volume. 2016.

BPJS Kesehatan. Panduan Praktis Prolanis (Program Pengelolaan Penyakit Kronis). BPJS Kesehatan. 2014.

Dahlan MS. Besar Sampel dan Cara Pengambilan Sampel dalam Penelitian Kedokteran dan Kesehatan. Edisi 3. Jakarta: Salemba Medika. 2010.

Nugraha DP, Dwiprahasto I, dan Atthobari J. Compliance Pengguna Antihipertensi di RSUP DR.Sardjito Yogyakarta (Periode Juli 2006-Juni 2009). JIK, Jilid 8, Nomor 2, September 2014, p. 70-75.

Heissam K, Abuamer Z, and El Dahshan N. Patterns and obstacles to oral antidiabetic medication adherence among type 2 diabetics in Ismailia, Egypt: a cross-section study. Pan African Medical Journal. 2015. 20:177.

Wilkinson S, Douglas I, Stirnadel FH, Fogarty D, Pokrajac A, Smeeth L, et al. Changing use of antidiabetic drugs in the UK: trends in prescribing 2000–2017. BMJ Open 2018;8.

Chu WM, Ho HE, Huang KH, Tsan YT, Liou YS, Wang YH et al. The Prescribing Trend of Oral Antidiabetic Agent for Type 2 Diabetes in Taiwan. Medicine. 2017. 96:43.

Honda RY, Takahashi Y, Mori Y, Yamashita S, Yoshida Y, Kawazu S, et al. Changes in Antidiabetic Drug Prescription and Glycemic Control Trends in Elderly Patients with Type 2 Diabetes Mellitus from 2005-2013: An Analysis of the National Center Diabetes Database (NCDD-03). Intern Med 57: 1229-1240. 2018.

McClintock HFDV, Morales KH, and Small DS. Patterns of Adherence to Oral Hypoglycemic Agents and Glucose Control among Primary Care Patients with Type 2 Diabetes. Behav Med. 2016; 42(2): 63–71.

Rasdianah N, Martodiharjo S, Andayani TM, dan Hakim L. Gambaran Kepatuhan Pengobatan Pasien Diabetes Melitus Tipe 2 di Puskesmas Daerah Istimewa Yogyakarta. Jurnal Farmasi Klinik Indonesia. 2016. Vol. 5 No. 4, p.249–57.

Nugraheni AY, Sari IP, dan Andayani TM. Pengaruh Konseling Apoteker dengan Alat Bantu Pada Pasien Diabetes. Jurnal Manajemen dan Pelayanan Farmasi. 2015. 225-32.

Perez LEG, Alvarez M, Dilla T, Gullen VG, Beltran DO. Adherence to Therapies in Patients with Type 2 Diabetes. Diabetes Ther. 2013 (4):175-94.


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