Relationship between Dietary Intake and High Sensitivity C-Reactive Protein (Hscrp) In Obese Adults
Abstract
Obesity is a body condition caused by an energy imbalance that is closely related
to diet. Obese people experience chronic low-grade inflammation in the body that can lead to
chronic disease due to the production of inflammatory markers from adipose tissue, one of
which is the acute phase protein C-reactive protein (CRP), which is closely related to diet.
The purpose of this study was to determine the relationship between dietary intake and
inflammatory markers (high sensitivity C-reactive protein, hs-CRP) in obese people. There
were 34 men and women aged 19-59 years with BMI 25.0 kg/m2 tested for hsCRP blood and
assessed dietary intake using the food frequency questionnaires (FFQ) method. The
relationship between dietary intake and hsCRP was assessed using the Spearman correlation.
Intake of calories, protein, fat, carbohydrates, fiber, PUFA, and cholesterol did not have a
significant relationship with hsCRP (p > 0.05). Dietary intake is not associated with hsCRP.
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Sheth J, Shah A, Sheth F, Trivedi S, Nabar N, Shah N, et al. The association of dyslipidemia and obesity with glycated hemoglobin. Clin Diabetes Endocrinol. 2015;1:1-7.
Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan Republik Indonesia. Riset Kesehatan Dasar (Riskesdas) 2013. Jakarta: Kemenkes RI; 2013.
Calder PC, Ahluwalia N, Brouns F, Buetler T, Clement K, Cunningham K, et al. Dietary factors and low-grade inflammation about overweight and obesity. Br J Nutr. 2011;106:1-78.
Eichelmann F, Schwingshackl L, Fedirko V, Aleksandrova K. Effect of plant-based diets on obesity-related inflammatory profiles: a systematic review and meta-analysis of intervention trials. Obes Rev. 2016;17(11):1067-79.
Lee H, Lee IS, Choue R. Obesity, Inflammation, and Diet. Pediatric Gastroenterology, Hepatology & Nutrition. 2013;16(3).
Lee RD, Nielman DC. Nutritional assessment. New York: McGraw-Hill; 2013.
Ross AC, Caballero B, Cousins RJ, Tucker KL, Ziegler TR. Modern nutrition in health and disease. Baltimore: Lippincott Williams & Wilkins; 2014.
Harray AJ, Boushey CJ, Pollard CM, Delp EJ, Ahmad Z, Dhaliwal SS, et al. A novel dietary assessment method to measure a healthy and sustainable diet using the mobile food record: protocol and methodology. Nutrients. 2015;7(7):5375-95.
Wan Y, Wang F, Yuan J, Li J, Jiang D, Zhang J, et al. Effects of Macronutrient Distribution on Weight and Related Cardiometabolic Profile in Healthy Non-Obese Chinese: A 6-month, Randomized Controlled-Feeding Trial. EBioMedicine. 2017;22:200-7.
Fisher G, Hyatt TC, Hunter GR, Oster RA, Desmond RA, Gower BA. Effect of Diet With and Without Exercise Training on Markers of Inflammation and Fat Distribution in Overweight Women. Obesity. 2010;19(6):1131-6.
Barbaresko J, Koch M, Schulze MB, Nothlings U. Dietary pattern analysis and biomarkers of low-grade inflammation: a systematic literature review. Nutr Rev. 2013;71(8):511-27.
Richard C, Couture P, Desroches S, Lamarche B. Effect of the Mediterranean Diet With and Without Weight Loss on Markers of Inflammation in Men With Metabolic Syndrome. Obesity. 2012;21:51-7.
Rachmi CN, Li M, Alison Baur L. Overweight and obesity in Indonesia: prevalence and risk factors-a literature review. Public Health. 2017;147:20-9.
Pujilestari CU, Nystrm L, Norberg M, Weinehall L, Hakimi M, Ng N. Socioeconomic inequality in abdominal obesity among older people in Purworedjo DIstrict, Central Java, Indonesia - a decomposition analysis approach. Int J Equity Health. 2017;16:214-24.
Pradeepa R, Anjana RM, Joshi SR, Bhansali A, Deepa M, Joshi PP, et al. Prevalence of generalized & abdominal obesity in urban & rural India--the ICMR-INDIAB Study (Phase-I) [ICMR- NDIAB-3]. Indian J Med Res. 2015;142(2):139-50.
Pujilestari CU, Nystrm L, Norberg M, Weinehall L, Hakimi M, Ng N. Socioeconomic inequality in abdominal obesity among older people in Purworejo District, Central Java, Indonesia a decomposition analysis approach. International Journal for Equity in Health. 2017;16(1).
Marques-Vidala P, Bochuda M, Bastardotb Fo, Lscherc T, Ferrerod Fo, Gaspoze J-M, et al. Association between Inflammatory and Obesity Markers in a Swiss Population-Based Sample (CoLaus Study). Obes Facts. 2012;5:734-44.
Popa C, Netea MG, Riel PLCMv, Meer JWMvd, Stalenhoef AFH. The role of TNF-? in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk. J Lipid Res. 2007;48:751-62.
Barbara J Nicklas WA, Stephen P Messier, Gary D Miller, Brenda WJH Penninx, Richard F Loeser, Shana Palla, Eugene Bleecker, and Marco Pahor. Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial. Am J Clin Nutr. 2004;79:54451.
Sharman MJ, Volek JS. Weight loss leads to reductions in inflammatory biomarkers after a very-low-carbohydrate diet and a low-fat diet in overweight men. Clin Sci. 2004;107:365-9.
DOI: https://doi.org/10.30596/bf.v6i2.6460
DOI (PDF): https://doi.org/10.30596/bf.v6i2.6460.g6042
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JURNAL BULETIN FARMATERA
Gedung Kampus 1 Universitas Muhammadiyah Sumatera Utara (UMSU) Lantai II, Laboratorium Farmakologi dan Terapi Fakultas Kedokteran UMSU Jalan Gedung Arca No. 53 Medan Sumatera Utara Indonesia, Kode Pos 20217.
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