Peran Acrosin Pada Fertilisasi Pria: Literature Review

Aidil Akbar

Abstract


Tahap fertilisasi diawali dengan adanya perjumpaan spermatozoa dan ovum, dimana sel sperma menebus dinding sel ovum mencapai zona pellusida, proses ini melibatkan protein khusus yang terdapat pada akrosom spermatozoa yang dikenal dengan acrosin berfungsi sebagai ezim proteolitik. Studi literatur ini bertujuan untuk membahas pentingnya peran acrosin dalam proses fertilisasi pada pria. Peneliti melakukan pencarian literatur dengan menggunakan aplikasi Google Scholar dengan menggunakan kata kunci Acrosin dan mencari literatur yang masuk dalam kriteria inklusi. Hasil penelusuran literatur dijumpai 15 literatur yang membahas tentang acrosin dari berbagai macam sudut pandang yang dihubungkan dengan proses fertilisasi.Acrosin merupakan protein enzimatik pada acrosome yang terdapat pada kepala sperma yang membatu sperma untuk mencapai zona pellusida sehingga dapat melakukan proses fertilisasi pada ovum.


Keywords


Acrosin, Fertilisasi

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References


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DOI: https://doi.org/10.30596/jph.v2i2.7597

DOI (PDF): https://doi.org/10.30596/jph.v2i2.7597.g5791

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Alamat Pengelola: Gedung Kampus 1 Universitas Muhammadiyah Sumatera Utara (UMSU) Lantai II, Laboratorium Farmakologi dan Terapi Fakultas Kedokteran UMSU Jalan Gedung Arca No. 53 Medan Sumatera Utara Indonesia, Kode Pos 20217.

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