Yield Analysis and Phytochemical Screening of Ethanol Extract of Phaleria macrocarpa Leaves

Ira Cinta Lestari, Dharma Lindarto, Syafruddin Ilyas, Tri Widyawati, Suryani Eka Mustika

Abstract


Phaleria macrocarpa leaves have the potential to be used as raw materials for medicines derived from natural ingredients, but research is needed to determine the content and efficacy of these plants. This study aims to analyze the yield and screening of the content of phytochemical compounds in the ethanolic extract of the Phaleria macrocarpa leaves. This research is a descriptive study. Extract yield analysis was performed by calculating the weight ratio of the extract divided by the simplicia multiplied by one hundred percent. Screening for the phytochemical content was carried out for compounds belonging to the class of flavonoids, saponins, tannins, alkaloids, steroids, and triterpenoids. The results of the calculation of the yield of the extract obtained were 14.58% and the results of the phytochemical test showed that the extract contained flavonoids, alkaloids, tannins, glycosides, saponins, and steroids.

Keywords


yield, ethanol extract, Phaleria macrocarpa, phytochemical screening

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References


Ali RB, Atangwho IJ, Kuar N, Ahmad M, Mahmud R, Asmawi MZ. In vitro and in vivo effects of standardized extract and fractions of Phaleria macrocarpa fruits pericarp on lead carbohydrate digesting enzymes. BMC Complement Altern Med. 2013;13(1):1-11. doi:10.1186/1472-6882-13-39

Easmin S, Sarker MZI, Ghafoor K, et al. Rapid investigation of ?-glucosidase inhibitory activity of Phaleria macrocarpa extracts using FTIR-ATR based fingerprinting. J food drug Anal. 2017;25(2):306-315.

Nugroho AA. Uji Toksisitas Subkronik Ekstrak Metanol Daging Buah Mahkota Dewa (Phaleria Macrocarpa) Terhadap Gambaran Histopatologis Mukosa Lambung Mencit. Published online 2019.

Sarveswaran R, Jayasuriya W, Suresh TS. In vitro assays to investigate the anti-inflammatory activity of herbal extracts a review. Published online 2017.

Mamatha S, Reddy PP, Voruganti A, Reddy VA, Bakshi V, Boggula N. Phaleria macrocarpa (scheff.) Boerl: A Phytochemical and Pharmacological.

Amir H, Murcitro BG, Ahmad AS, Kassim MNI. The potential use of Phaleria macrocarpa leaves extract as an alternative drug for breast cancer among women living in poverty. Asian J Poverty Stud. 2017;3(2).

Meiyanti M, Margo E, Pusparini P, Merijanti LT, Lesmana A. Hypoglycemic effect of Phaleria macrocarpa (Scheff.) Boerl dry extract in healthy adults. Universa Med. 2018;37(3):195-202.

Lestari IC. Efek Antidiabetik Ekstrak Etanol Daun Mahkota Dewa (Phaleria Macrocarpa) Pada Tikus Diabetes Yang Diinduksi Streptozotosin. Biomedika. 2018;10(2):94-101.

Sulistyoningrum E, Pradipta DM, Fanana S, Haikhah JA, Putro MDH. Protective effect of Phaleria macrocarpa (Scheff.) Boerl extract on the testicular damage of streptozotocin and nicotinamide-induced type 2 diabetic rats. J Appl Pharm Sci. 2018;8(6):139-146.

Wijanarko H. Aktivitas Phalerin hasil isolasi dari daun Mahkota dewa (Phaleria macrocarpa Scheff) Boerl) sebagai pemacu fagositosis makrofag dan antiradikal in vitro. Univ Gadjah Mada. Published online 2005.

Ghufron M, Soesatyo MM, Haryana S. The effects of Ethanol extract isolated from Phaleria macrocarpha on NK1. 1 activity. Berkala Ilmu Kedokteran. 2008;40(3):109-118.

Saifudin A, Rahayu V, Teruna HY. Texbook standardisasi bahan obat alam. Ed pertama Yogyakarta Press Univ Gajah Mada. 2011;50(1):1-26.

Hartini YS, Wahyuono S, Widyarini S, Yuswanto A. Uji Aktivitas Fagositosis Makrofag Fraksi-fraksi dari Ekstrak Metanol Daun Sirih Merah (Piper crocatum Ruiz & Pav.) Secara In Vitro (Phagocytic Macrophage Activity of Fractions from Methanolic Leaf Extract of Red Betel (Piper crocatum Ruiz & Pav.) In Vitr. J Ilmu Kefarmasian Indones. 2012;11(2):108-115.

Koirewoa YA, Fatimawali, Wiyono WI. Isolasi dan Identifikasi Senyawa Flavonoid Dalam Daun Beluntas (Pluchea indica L.). Pharmacon. 2012;1(1):47-52.

Azis T, Febrizky S, Mario AD. Pengaruh Jenis Pelarut Terhadap Persen Yield Alkaloid dari Daun Salam India (Murraya Koenigii). Tek Kim. 2014;20(2):1-6.

Dewatisari WF, Rumiyanti L, Rakhmawati I. Rendemen dan Skrining Fitokimia pada Ekstrak Daun Sanseviera sp. J Penelit Pertan Terap. 2018;17(3):197. doi:10.25181/jppt.v17i3.336

Depkes RI. Materia Medika Indonesia. Jilid VI Jakarta Dep Kesehat RI Hal. 1995;319325.

Kurang RY, Malaipada NA. Uji Fitokimia Dan Aktivitas Antioksidan Ekstrak Metanol Daging Buah Mahkota Dewa (Phaleria Macrocarpa). Sebatik. 2021;25(2):767-772. doi:10.46984/sebatik.v25i2.1353

Agustina W, Nurhamidah N, Handayani D. Skrining fitokimia dan aktivitas antioksidan beberapa fraksi dari kulit batang jarak (Ricinus communis L.). Alotrop. 2017;1(2).

Yuandani Y, Yohana M, Marianne M. Aktivitas Analgetik Ekstrak Etanol Daun Pugun Tanoh (Picria Fel-Terrae Lour) Pada Mencit (Mus Musculus). In: Talenta Conference Series: Tropical Medicine (TM). Vol 1. ; 2018:167-171.

Fiana N, Oktaria D. Pengaruh kandungan saponin dalam daging buah mahkota dewa (Phaleria macrocarpa) terhadap penurunan kadar glukosa darah. J Major. 2016;5(4):128-132.

Easmin MS, Sarker MZI, Ferdosh S, et al. Bioactive compounds and advanced processing technology: Phaleria macrocarpa (sheff.) Boerl, a review. J Chem Technol Biotechnol. Published online 2014. doi:10.1002/jctb.4603

Fariza N, Fadzureena J, Zunoliza A, A LC, K Y Pin, I A. Anti-inflamatory Activity of the Mayor Compound from Methanol Extract of Phaleria macrocarpa Leaves. J Appl Sci. 2012;12(11):1195-1198. doi:10.3923/jas.2012.1195.1198

Djati S. Anti-breast cancer potential activity of Phaleria macrocarpa (Scheff.) Boerl. leaf extract through in silico studies. J Pharm Pharmacogn Res. 2021;9(6):824-845.




DOI: https://doi.org/10.30596/bf.v8i1.11724

DOI (PDF): https://doi.org/10.30596/bf.v8i1.11724.g8475

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