Effects of Corn Silk (Stigma Maydis) Against Blood Glucose Levels of Type 2 Diabetes Mellitus Patients

Laurencia Alimin

Abstract


According to WHO, in 2017 there are an estimated 425 million sufferers of diabetes mellitus. Indonesia is placed in the seventh rank in the world in 2015, with an estimated 10 million sufferers. To reduce the prevalence of type 2 diabetes mellitus, improvements need to be made, such as lifestyle modification and treatment. Most anti-diabetic drugs have high side effects. Corn silk is one of the natural ingredients that contain flavonoids, which can reduce blood fat levels. The dose of corn silk of 500 mg/kg BW is the best substance against diabetic rats from excessive weight loss. Therefore, corn silk can be calculated to have an anti-diabetic effect by using lipids, eliminating free radicals, and increasing antioxidant capacity.


Keywords


Diabetes Mellitus, Cornsilk, Antidiabetic

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References


International Diabetes Federation (IDF) [database on the internet]. IDF Diabetes Atlas Eight Edition. C2017 [cited 2019 Aug 19]. Available from: https://www.diabetesatlas.org

American Diabetes Association(ADA). Classification and diagnosis of diabetes: standards of medical care in diabetes. Diabetes Care. 2019; 42(1):1328.

World Health Organization (WHO). Diabetes. C2018 [cited 2019 Aug 19]. Available from: https://www.who.int

World Health Organization (WHO). Diabetes Fakta dan Angka. C2016 [cited 2019 Aug 19]. Available from: https://www.who.int

Kementerian Kesehatan Republik Indonesia (Kemenkes RI). Hasil utama riskesdas 2018. Jakarta (Indonesia): Kemenkes RI; 2018.

Zhang Y, Wu L, Ma Z, Cheng J, Liu J. Anti-diabetic, anti-oxidant and anti-hyperlipidemic activities of flavonoids from corn silk on STZ-induced diabetic mice. Molecules. 2016;21(7):111.

Hasanudin K, Hashim P, Mustafa S. Corn silk (Stigma maydis) in healthcare: a phytochemical and pharmacological review. 2012;17(1): 9697715.

Purnamasari D. Diagnosis dan klasifikasi diabetes melitus. In: Sudoyo AW, Setiyohadi B, Alwi I, Simadibrata M, Setiati S. Buku Ajar Ilmu Penyakit Dalam Edisi Keenam Jilid II. Jakarta: Interna Publishing; 2014. p. 232530.

Soelistijo SA, Novida H, Rudijanto A, Soewondo P, Suastika K, Manaf A, et al. Konsensus pengelolaan dan pencegahan diabetes melitus tipe 2 di indonesia 2015. Jakarta: PB Perkeni; 2015.

Wijayanti F, Ramadhian MR. Efek rambut jagung (Zea mays) terhadap penurunan kadar kolesterol dalam darah. Majority. 2016; 5(3)915.

Guo J, Liu T, Han L, Liu Y. Nutrition & metabolism the effects of corn silk on glycaemic metabolism. Nutrition & Metabolism 2009;6:16.

Wirasutisna KR, Fidrianny I, Rahmayani A. Telaah kandungan kimia rambut jagung (Zea mays L.). Acta Pharmaceutica Indonesia. 2012;37(1):58.

Hidayah N, Nisak R. Pengaruh pemberian teh rambut jagung (Zea Mays L) terhadap kadar gula darah penderita diabetes tipe 2. Profesi. 2019;16(2):109.

Ajie RB. White dragon fruit (Hylocereus undatus) potential as diabetes mellitus treatment. Majority. 2015;4(1):6972.

Mursiany A. Efektivitas infusa rambut jagung (Zea mays L.) sebagai antidiabetes pada mencit swiss webster yang diinduksi dengan. Pena. 2019;33(1):3743.




DOI: https://doi.org/10.30596/bf.v5i2.3989

DOI (PDF): https://doi.org/10.30596/bf.v5i2.3989.g4186

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