FETIFORM TERATOMA: GOD-CREATED MAN WITHOUT FATHER?

Humairah Medina Liza Lubis, Mohd Nadjib Dahlan Lubis

Abstract


Fetiform teratoma, also known as homunculus, represents one of the most extraordinary and diagnostically challenging entities in surgical pathology. Fetiform teratomas result from neoplastic processes of germ cells, while fetus-in-fetu arises from aberrant embryogenesis, specifically the inclusion of a parasitic monozygotic twin, and common locations of fetiform teratoma include the ovaries, retroperitoneum, and sacrococcygeal region, with clinical presentations varying from neonatal masses to pelvic pain in adults. We present a case of a 27-year-old Indonesian woman (gravida 1, para 0), Karo ethnicity, presented with abdominal enlargement. She underwent a laparotomy and left ovarian cystectomy. The ovarian cyst was as described as a10 x 9 x 7 cm cyst, smooth, brown, reddish-black cyst, when dissectioned resembles a 8.5 x 7 x 5 cm fetus. On microscopic examination it was found head  appeared  bones, cartilage, nerves, ganglia, and choroid plexus; back appeared skin, skin adnexa, and fat; abdomen appeared umbilical cord orifice, digestive tract with complete muscular tube; and cross section of umbilical cord appeared digestive tract and 2 blood vessels. This serves as further evidence of the truth of the sacred verses of the Qur’an, which state that it is not impossible for a child to be born to a mother who has never been touched by a man, for if Allah wills it by merely saying, ‘Be,’ then so shall it be. Scientific views are also presented which prove the truth and relevance of Surah Al-Mu’minun verses 12-16, Surah Ath-Thariq verses 6-7, and Surah Al-‘Alaq verses 1-2 to the creation of humankind.


Full Text:

PDF

References


AlJahsh, M. A. I. (2024). Science and Islamic ethics : Navigating artificial womb technology through Quranic principles. Heliyon, 10(17), e36793. https://doi.org/10.1016/j.heliyon.2024.e36793

Cáceres-Farfán, L., Cubas, W. S., Albán, F., Mantilla-Vásquez, J., Mayta-Rodríguez, J., & Mendoza-Guerra, K. (2023). Thoracic Fetiform Teratoma: A Case Report of a Very Rare Entity in a Peruvian Hospital Ludwig. Journal of Chest Surgery, 56(4), 282–285.

Carli, G. J. de, & Pereira, T. C. (2017). On human parthenogenesis. Medical Hypotheses, 106, 57–60. https://doi.org/10.1016/j.mehy.2017.07.008

Dadach, Z. E. (2024). Tawheed-Based Science. Retrieved from https://www.researchgate.net/publication/378078220_Tawheed-Based_Science/references

Faizi, F. R., & Rasouly, N. (2020). Lumbar fetiform teratoma ; a case report. Radiology Case Report, 15, 837–840. https://doi.org/10.1016/j.radcr.2020.03.023

Gedamu, D., Wondafrash, M., & Berhanu, M. (2025). Ovarian Fetiform Teratoma in 38 Years Nulliparous Woman.pdf. Clinical Case Reports, 13(e70029), 1–4.

Ghoneim, K. (2016). INSIGHT INTO THE CONTEMPORARY INTERPRETATION OF QUR’ANIC AYAT OF NATURAL SCIENCES : DISCUSSION AND DEBATE. Academic Journal of Scientific Miracles, 37(4), 57–77. https://doi.org/10.19138/miracles.37.4

Goldberg, H. R., Allen, L., & Kives, S. (2017). Fetiform Teratoma in the Ovary of a 7-Year-Old Girl_ A Case Report - ScienceDirect. Journal of Pediatric and Adolescent Gynecology, 30(2), 256–258.

Greenberg, J. A., & Clancy, T. E. (2008). Fetiform Teratoma ( Homunculus ). REVIEWS IN OBSTETRICS & GYNECOLOGY, 1(3), 95–96.

Hegazy, A. A., Al-qtaitat, A. I., & Hegazy, R. A. (2023). A new hypothesis may explain human parthenogenesis and ovarian teratoma : A review study. International Journal of Reproductive BioMedicine, 21(4), 277–284.

Liu, Y., Fan, H., Kang, X., Hao, Y., Wang, N., Zheng, H., … Scott, M. P. (2024). A rare germline BMP15 missense mutation causes hereditary ovarian immature teratoma in human. PNAS, 121(10), 1–10. https://doi.org/10.1073/pnas.

Miura, K., Kurabayashi, T., Satoh, C., Sasaki, K., Ishiguro, T., Yoshiura, K., & Masuzaki, H. (2017). Fetiform teratoma was a parthenogenetic tumor arising from a mature ovum. Journal of Human Genetics, 62, 803–808.

Mohammad, A. (2020). QUR’AN ON EMBRYOLOGY: A STUDY OF QUR’ANIC AND MODERN CONCEPT OF HUMAN DEVELOPMENT. Journal of Islam and Science, 7(1), 31–38.

Pace, S., Sacks, M. A., Goodman, L. F., Tagge, E. P., & Radulescu, A. (2021). Antenatal Diagnosis of Retroperitoneal Cystic Mass : Fetiform Teratoma or Fetus in Fetu ? A Case Report. American Journal of Case Reports, 22(e929247), 1–5. https://doi.org/10.12659/AJCR.929247

Palo, S., Mangla, M., Motwani, R., Gabbeta, S., Mishra, M., & Kanikaram, P. K. (2025). Fetiform teratoma: a systematic review with insights into concepts and controversies in differentiating it from fetus-in-fetu. Pediatric Surgery International, 41(1). https://doi.org/10.1007/s00383-025-06087-7

Quran Gallery App. (n.d.). Sign in Islam - Quranic Concept of Ayah _ Divine Revelation & Miracles. Retrieved from https://www.qurangallery.app/topics/ayah-sign-islamic-divine-revelation-miracles-quran

Sima, M., Kumar, B. S., Gourisankar, K., & Charan, B. S. (2008). Ovarian mature cystic teratoma containing a structure resembling a miniature human body (Homunculus) _ The Journal of Obstetrics and Gynaecology of India. The Journal of Obstetric & Gynecology, 58(3).




DOI: https://doi.org/10.3059/insis.v0i0.29966

DOI (PDF): https://doi.org/10.3059/insis.v0i0.29966.g15233

Refbacks

  • There are currently no refbacks.