Komorbiditas Psikiatri pada Pasien dengan Penyakit Parkinson
Abstract
Penyakit Parkinson (PD) adalah penyakit neurodegeneratif, meningkat lebih cepat dibanding gangguan neurologis lain serta. PD memiliki trias klasik gejala motorik dan gejala non motorik, dimana gangguan psikiatri merupakan salah satu diantara gejala non motorik. Beberapa gangguan psikiatri yang dapat menyertai PD yaitu gangguan depresi, kecemasan, apatis, obsesif kompulsif, gangguan tidur, demensia serta gangguan psikosis. Gangguan ini berkontribusi signifikan terhadap kecacatan dan kualitas hidup yang buruk sehingga diperlukan pemahaman terhadap faktor resiko dan patofisiologi dari gangguan-gangguan psikiatri tersebut.
Full Text:
PDF (Bahasa Indonesia)References
Armstrong MJ, Okun MS. Diagnosis and Treatment of Parkinson Disease: A Review. JAMA - J Am Med Assoc. 2020;323(6):548–60.
Kouli A, Torsney KM, Kuan W-L. Parkinson’s Disease: Etiology, Neuropathology, and Pathogenesis. In: Stoker TB, Greenland JC, editors. Parkinson’s Disease Pathogenesis and Clinical Aspects. 1st ed. Brisbane, Australia: Codon Publication; 2018. p. 3–26.
Galts CPC, Bettio LEB, Jewett DC, Yang CC, Brocardo PS, Rodrigues ALS, et al. Depression in neurodegenerative diseases: Common mechanisms and current treatment options. Neurosci Biobehav Rev [Internet]. 2019;102(February):56–84. Available from: https://doi.org/10.1016/j.neubiorev.2019.04.002
Jankovic J, Tan EK. Parkinson’s disease: etiopathogenesis and treatment Journal of Neurology, Neurosurgery & Psychiatry 2020;91:795-808
Meloni M. , Puligheddu M. , Carta M. , Cannas A. , Figorilli M. , & Defazio G.. Efficacy and safety of 5‐hydroxytryptophan on depression and apathy in parkinson's disease: a preliminary finding. European Journal of Neurology 2020;27(5):779-786. https://doi.org/10.1111/ene.14179
Schrag A, Taddei RN. Depression and Anxiety in Parkinson’s Disease [Internet]. 1st ed. Vol. 133, International Review of Neurobiology. Elsevier Inc.; 2017. 623–655 p. Available from: http://dx.doi.org/10.1016/bs.irn.2017.05.024
Mele B, Merrikh D, Ismail Z, Goodarzi Z. Detecting Apathy in Individuals with Parkinson’s Disease: A Systematic Review. J Parkinsons Dis. 2019;9(4):653–64.
Liou Y, Bai YM, Mu-Hong C, Chih-Ming C, Tzeng-Ji C, Shih-Jen T. Obsessive-Compulsive Disorder and Risk of Parkinson Disease: A Nationwide Longitudinal Study. Psychosomatic Medicine. 2022; 84(9):p 1096-1102. DOI: 10.1097/PSY.0000000000001120
Lo Monaco MR, Di Stasio E, Zuccalà G, Petracca M, Genovese D, Fusco D, et al. Prevalence of Obsessive-Compulsive Symptoms in Elderly Parkinson Disease Patients: A Case-Control Study. Am J Geriatr Psychiatry. 2020;28(2):167–75.
Stefani A, Högl B. Sleep in Parkinson's disease. Neuropsychopharmacology. 2020;45(1):121-128. doi:10.1038/s41386-019-0448-y
Sveinbjornsdottir S. The clinical symptoms of Parkinson’s disease. J Neurochem. 2016;318–24.
Sobreira-Neto MA, Pena-Pereira MA, Sobreira EST, Chagas MHN, de Almeida CMO, Fernandes RMF, et al. Chronic Insomnia in Patients With Parkinson Disease: Which Associated Factors Are Relevant? J Geriatr Psychiatry Neurol. 2020;33(1):22–7.
Hanagasi HA, Tufekcioglu Z, Emre M. Dementia in Parkinson's disease. J Neurol Sci. 2017;374:26-31. doi:10.1016/j.jns.2017.01.012
Schneider RB, Iourinets J, Richard IH. Parkinson’s disease psychosis: presentation, diagnosis and management. Neurodegener Dis Manag. 2017;7(6):365–76.
DOI: https://doi.org/10.30596/jih.v5i2.19749
Refbacks
- There are currently no refbacks.
Fakultas Kedokteran
Universitas Muhammadiyah Sumatera Utara
Jln.Gedung Arca No. 53 Medan 20217
Telp/HP/Whatsapp: +62 8112570085, +62 857-6248-0974
Website : http://jurnal.umsu.ac.id/index.php/JIH/index
Email : implementahusada@umsu.ac.id